Search on: TYPE I SITE-SPECIFIC DEOXYRIBONUCLEASES 
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Descriptor English:   Deoxyribonucleases, Type I Site-Specific 
Descriptor Spanish:   Desoxirribonucleasas de Localización Especificada Tipo I 
Descriptor Portuguese:   Desoxirribonucleases de Sítio Específico do Tipo I 
Synonyms English:   DNase, Site Specific, Type I
Deoxyribonucleases, Type I, Site Specific
Deoxyribonucleases, Type I, Site-Specific
Site-Specific DNase, Type I
Type I Site Specific DNase
Type I Site Specific Deoxyribonucleases
Type I Site-Specific DNase
Type I Site-Specific Deoxyribonucleases
Deoxyribonucleases, Type I Site Specific
Site Specific DNase, Type I
DNA Restriction Enzymes, Type I
Restriction Endonucleases, Type I
Type I Restriction Enzymes
DNase, Site-Specific, Type I  
Tree Number:   D08.811.150.280.250
D08.811.277.352.335.350.300.250
D08.811.277.352.355.325.300.250
Definition English:   Enzyme systems containing three different subunits and requiring ATP, S-adenosylmethionine, and magnesium for endonucleolytic activity to give random double-stranded fragments with terminal 5'-phosphates. They function also as DNA-dependent ATPases and modification methylases, catalyzing the reactions of EC 2.1.1.72 and EC 2.1.1.73 with similar site-specificity. The systems recognize specific short DNA sequences and cleave at sites remote from the recognition sequence. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.3. 
Indexing Annotation English:   DF: DNASE SS I
History Note English:   89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   23602 
Unique Identifier:   D015253 

Occurrence in VHL: 		 

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